Synthesis and antibacterial activity of Schiff Base Complexes of Si (IV)

In the present work synthesis, characterization, and antibacterial evaluation of organosilicon (IV) complexes of a class of amino-acid-based Schiff base which have been prepared by the interaction of ethoxytrimethylsilane with the Schiff bases (N OH) in 1?:?1 molar ratio have been studied which have been characterized on the basis of elemental analyses, molecular weight determinations and conductivity measurements. A few representative complexes have also been screened for their bactericidal activity and found to be quite active in this respect against bacteria (Bacillus subtilis, Escherichia coli, Streptococcus albudencus, and Staphylococcus aureus. Pseudomonas aeroginosa). The complexes were found to be more potent as compared to the ligands.