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Optimizing Treatment of Patients with Co-Existing Cardiorespiratory Pathology by Administration of Anti-Inflammatory Roflumilast and Cardioprotective Agent Quercetin

Journal: Galician Medical Journal (Vol.21, No. 3)

Publication Date:

Authors : ; ;

Page : 65-69

Keywords : chronic obstructive pulmonary disease; ischemic heart disease; inflammatory biomarkers;

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Abstract

The article discusses the research findings on the effectiveness and safety of combination treatment with roflumilast and quercetin in aggravated chronic obstructive pulmonary disease (COPD) along with a co-occurring comorbid ischemic heart disease (IHD). Clinical evidence highlights the effect of combination of roflumilast and quercetin as a part of the basic treatment of COPD and conventional treatment of IHD on clinical symptomatology, C-reactive protein levels, and α2-macroglobulin in plasma. It was found that a complex therapy leads to a substantial improvement of patients’ clinical condition owing to reduced systemic inflammatory activation and improved immune defense, which decreases incidence of cardiovascular complications.

Last modified: 2015-11-25 17:39:02