THE DIAGNOSTIC SIGNIFICANSE OF P53-ONCOPROTEIN AND KI.67 PROLIFERATIVE LEVEL EXPRESSION IN SEROUS AND MUCINOUS BORDERLINE OVARY TUMORS

These article is dedicate to investigations of the potential malig-nance probability, metastasis possibility development, clinical survival and prognosis of serous and mucinous borderline ovarian tumors, that are considered as transitional link between benign and malignant tumors of this localization with immunomorphological methods, including monoclonal antibodies to p53 and Ki?67. The most clinical samples showed the postoperational material with Ki67+/p53- status, what argument a relatively favorable prognosis and a low ten-dency to malignanization, but the Ki67+/p53+ status, has received a more careful samples requires, that need in detailed studying and probable menacing of maligni-zation and metastasis development.