Kaposi Sarcoma of Spleen in HIV-Negative Patient Detected with F-18 FDG PET/CT

We report a case of Kaposi sarcoma (KS) who presented with unusual clinical features. The unusual clinical features were abscence of detectable HIV, absence of cutaneous lesion and presence of a splenic mass. F-18 FDG PET/CT demonstrated a spleen mass lesion with FDG uptake with SUVmax 7.0. This lesion was confirmed by ultrasonography guided biopsy. The lesion was consistent with KS. F-18 FDG PET/CT may be instrumental in establishing a diagnosis of the splenic KS.