Fast dissolving tablets as a novel boon for lipophilic drugs

The objective of this paper was to review the information about Fast dissolving tablet. Methods to improve patient’s compliance have always attracted scientists towards the development of fancy oral drug delivery systems. Among them, fast dissolving drug delivery systems (FDDDS) have acquired an important position in the market by overcoming previously encountered administration problems. FDDDS have the unique property of rapidly disintegrating and/or dissolving and releasing the drug as soon as they come in contact with saliva, thus obviating requirement of water during administration. This is seen to afflict nearly 35% of the general population and associated with a number of conditions like parkinsonism, mental disability, motion sickness, unconsciousness and unavailability of water. To overcome such problems, certain innovative drug delivery systems, like ‘Fast Dissolving Tablets’ (FDT) have been developed. FDTs dissolve in saliva within a few seconds, when put on tongue. Such FDTs can be administered anywhere and anytime, without the need of water and are thus quite suitable for children, elderly and mentally disabled patients. This article describes the existing techniques for fast dissolving oral preparation, highlights their manufacturing process, various modifications in the conventional technique, evaluation parameter, future trends for these evolving forms and patients counseling points for FDDTs.