Antioxidant activity of methanolic root extract of Gynochthodes ridsdalei Razafim. & B.Bremer (Rubiaceae), an endemic, endangered medicinal plant of Southern Western Ghats, India
Journal: Journal of Pharmacy Research (Vol.9, No. 6)Publication Date: 2015-06-11
Authors : Renji R.Nair; A.Gangaprasad;
Page : 343-347
Keywords : Gynocthodes ridsdalei; antioxidant; radical scavenging.;
Abstract
Antioxidant activity of methanolic root extract of Gynochthodes ridsdalei ( Syn: Morinda reticulata) was studied for its free radical scavenging property on different in vitro models such as Reducing power, DPPH, nitric oxide radical scavenging, hydroxyl radical scavenging and superoxide radical scavenging assays. The extract showed good free radical scavenging ability in all in vitro models except in superoxide scavenging assays, which showed only 43.3% in 1000?g/ml. IC 50 values were found to be 0.12, 0.43, 0.33 mg/l in DPPH, Nitric oxide, superoxide respectively.
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