STUDY OF PRESCRIBING PATTERN OF ANTIBIOTICS IN THE MANAGEMENT OF VARIOUS INFECTIOUS DISEASES IN WARANGAL REGION

The main objective of the study is to assess the prescribing patterns of antibiotics Prescribing frequency of Antibiotics according to Diagnosis, Mono therapy / Dual therapy / Triple therapy & their treatment outcomes& to know prescribing frequency of Emperical, prophylactic or definative therapy of antibiotics in the management of various infectious diseases. This is a prospective observational study conducted in Warangal hospital, Vishwas super specialty hospital, Varma Chest hospital, SVR Multi specialty hospital & Adithya hospitals of Warangal region between march 2014 and September 2014. Data was obtained from patient’s interviews and medical records of 200 patients admitted in the hospital. Of the 200 patients studied the predominant age group was 30-40years (22%).The most frequent infectious diseases are Gastrointestinal infections in 41 patients is 20% and Urinary tract infections in 41 patients is 20% and the least was skin infection(Herpes Zoaster) standing with 1%. And the most frequently used antibiotics belongs to the class of cephalosporins (45.37%) , flouroquinolones -ofloxacin & ciprofloxacin (14.09%) anti anerobicsmetronidazole & ornidazole (12.33%) followed by pencillins-amoxacillin & ampicillin (11.89%) and tetracyclines ?doxycycline (9.471%). Studies revealed that 63 patients (32%) are treated with triple and 63 patients (31%) with dual therapy followed multiple therapy 52 patients (26%) and mono therapy 22 patients (11%). In mono therapy the most frequently used antibiotics were ceftriaxone with 13 patients (59%) and ofloxacin with 3 patients (14%). In dual therapy two types are being prescribed as (Dual combination therapy) in 37 patients and individual therapy (mono + mono) in 26 patients of which in dual combination therapy. In triple (Dual + mono) therapy (cefoperazone + salbactam) combination with doxycycline is the most frequently prescribed drug in 7 patients (18%) and (cefoperazone + salbactam) + ofloxacin combination in 3 patients (8%). In our study multiple therapy was prescribed in about 52 patients of which (amoxicillin and clavulanicacid)+(ceftriaxone + tazobactam) combination was used in about 2 patients (4%). Present study reveals that definitive therapy was prescribed in 164 patients (82%) following prophalytic therapy in 26 patients (13%) and empirical therapy in 10 patients.