SYNTHESIS AND CHARACTERISATION OF VARIOUS AROMATIC AND HETEROCYCLIC DERIVATIVES OF 2-PYRAZINOYL HYDRAZIDE

The chelating ligands are used to prepare chelates with a number of metal ions.The chelting ligands of various aldehydic derivatives possess hard donor sites which are capable of forming complex compounds with hard metals. 2- Pyrazinoyl hydrazide acts as good chelating ligand for various metal ions. The derivatives of 2-pyrazinoyl hydrazide with various aldehydes may be prepared which may be considered by analytical chemists for formation of chelates with metal ions. These chelates may be tested for antibacterial, fungicidal, anti- inflammatory and analgesic activities because the Mannich bases possess all these activities. Considering these observations here we have undertaken the preparation of 2-pyrazinoyl hydrazide and its derivatives with various aromatic and heterocyclic aldehydes. The present paper deals with the synthesis, purification and structure elucidation of derivatives of various aromatic and heterocyclic aldehydes with 2-pyrazinoyl hydrazide which can be used as chelating ligands.