PCOS - A REVIEW

Polycystic ovary syndrome (PCOS), characterized by chronic anovulation and hyperandrogenism, is common in women of childbearing age. Most of these women also have insulin resistance, and insulin sensitizing agents--metformin and the thiazolidinediones-- can restore ovulation and often fertility. Treatment of hirsutism and depression are important components of therapy. The increased risk for uterine cancer because of unopposed estrogen can be managed with progestin therapy. Women with PCOS are also at greater risk for both type 2 diabetes and cardiovascular disease.