ROLE OF PURISHADHARA KALA CALCIUM & BILIRUBIN METABOLISM

In Ayurveda, (Kala) has been defined as the internal limiting layer in the (DhatwAshayas.) It can be considered as a membrane or a layer which separates two entities in the body. Seven Kalas are mentioned in this science, of which( Purishadhara Kala )is the fifth one. It is situated around spleen liver and large intestine(Yakrut, Aantra, Unduka and PakwAshaya. )It is also called as the (Maladhara Kala) Acharya Dalhana has stated that, the ( Purishdhara Kala is Asthidhara) Kala. As per modern science, the smooth muscle layer of the intestine, contain calcium- sodium ion channels in large number. These channels function mainly as the initiators of smooth muscle contractions in the intestine. This layer can be considered as one of the internal layer of (Purishadhara Kala). The extra cellular fluid is the source of calcium for these ion channels. Acharya Sushruta has explained the seven stages of poison ( i.e Visha Vegas.) and this poison takes the (Ashraya in these Kalas )for exhibiting the symptoms of poisoning. By this we can correlate( Purishadhara Kala to Asthidhara Kala, )and also the role of calcium ion channels in the pakwashaya . It explains the( Ashraya-Ashrayee Sambandha of Vata Dosha )and (Asthi Dhatu )in the intestine (PakwAshaya).