ANALYSIS OF FUNCTIONAL MYOCARDIUM DISORDERS IN ELDERLY AND SENILE PATIENTS WITH COMPLICATED ACUTE CHOLECYSTITIS AFTER CHOLECYSTECTOMY

Summary. A comparative analysis of functional myocardium disorders was performed in 517 patients aged 60 years and older with concomitant coronary artery diesease (CAD) after surgical treatment for complicated acute cholecystitis (AC). Patients were divided into three groups. Traditional cholecystectomy (TCE) was performed in the comparison group №1 (n = 178), laparoscopic cholecystectomy (LCE) was performed in comparison group №2, and, LCE with bacteriophage therapy ? in the main group. The functional state of the cardiovascular system was evaluated according to 24-hour Holter monitoring of the electrocardiogram (ECG). Application of bacteriophage therapy in patients with complicated AC and concomitant coronary artery diesease (CAD) allowed to stop the inflammatory process in the abdominal cavity more quickly, reducing the manifestations of endogenous intoxication (EI), reducing the degree of impairment of repolarization in the myocardium and hypoxic damage that had positive impact on the hemodynamic conditions (in particular on reducing the heart rate (HR)) and, in turn, led to decrease of myocardial repolarization disorders