Correlation of Sex and Remission of Acute Lymphoblastic Leukemia-L1 (ALL-L1) in Children

Introduction: Acute Lymphoblastic Leukemia (ALL) is a malignancy that often is found in children with peak incidence of 2-5 years. The symptoms and biological factors affect the ALL prognosis; age, leucocyte count, sex, nutitional state, ALL phenotype, CNS infiltration, chromosome abnormalities, and early response to chemotherapy. Objective: The aim of this study was to determine the role of sex on the patient’s remission with ALL-L1. Methods: The retrospective cohort study was conducted to determine the role of sex on the patient’s remission with ALL-L1. The study was conducted in the pediatric ward of Dr. Wahidin Sudirohusodo hospital in Makassar from March until November 2014. The cases were taken from the pediatric ward who met both the inclusion and exclusion criteria. The data was taken from the patient’s medical records related to the study. Results: Revealed of 70 cases who met the criteria was consist of 42 males and 28 females. Frequency of remission in males group was 41 (97.6%) and in females group was 27 (96.4%). The statistical analysis revealed that there was no significant difference between sex and remission, as it was shown by p = 0.643 (p>0.05). Conclusion: Sex did not have any effects on the frequency of remission in children with ALL-L1 in Dr. Wahidin Sudirohusodo hospital. The frequency of remission in males group was 97.6%, and in females group was 96.4%.