PRIMARY MYXOID EPITHELIOID EXTRA-INTESTINAL GASTROINTESTINAL STROMAL TUMOR OF GREATER OMENTUM

Background: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract believed to originate from interstitial cells of Cajal. Development of GISTs outside the gastrointestinal system, called as Extra-intestinal gastrointestinal stromal tumor (EGISTs) is rare. Incidence of primary GIST in the greater omentum has been reported to be <1%. Case report: A rare case of EGIST in an 89 year old woman, arising from the greater omentum is presented here. In this patient EGIST was primary and of epithelioid type with prominent myxoid change. Conclusion: Recognition of myxoid epithelioid variant of EGIST is important as it is defined as a separate entity with availability of molecular targeted therapy.