Regeneration of Human Dental Pulp: A Myth or Reality? A case report

Histological studies of regenerated tissue in the pulp canal space following successful revascularisation procedure in human teeth without extracting them are very rare. This case report describes the histological findings of tissue formed within the canal space of tooth on which revascularisation procedure was attempted. An 11 year old girl, reported 3 years ago with an injury in her upper front region with immature, non vital maxillary central incisors. Revascularization was attempted. Patient reported at the age of 14 years with pain and sensation of hot and cold in one of the treated teeth. On examination secondary caries were present and signs of maturogenesis were observed radiographically. On re-entering the canal the regenerated tissue was obtained and analysed histologically. H/E staining revealed dominantly fibrous connective tissue with spindle shaped fibroblasts in the apical region and numerous RBC’s and inflammatory cells in the coronal region. The connective tissue was not well organized.