A comparative evaluation of the Solubility Rate and Antibacterial Effect of 2 endodontic sealers after the incorporation of Amoxicillin and Clavulanic Acid

The purpose of this study was to evaluate the Antibacterial Effect against Enterococcus faecalis(E.faecalis) and Solubility rate of a Zinc Oxide-Eugenol based (ZnoE) (PrimeDent) and a resin based (AH Plus) sealer after the incorporation of an Amoxycillin and Clavulanic Acid (ACA) (AugmentinR). The antibacterial activity was evaluated by the Direct Contact Test (DCT) when AH plus and Zinc Oxide-Eugenol based sealer comes in contact with Enterococcus faecalis. Growth of the microorganisms was measured every hour for first 8 hours at the end of the 1st day, 3rdday, and 7th days. To evaluate the Rate of Solubility, samples were weighed before and after placing them in a still water bath. Samples were weighed on a Precision Balance Machine at the end of the 1st day, 3rd day and 7th day. The resulting weight loss was taken to be the parameter for the Solubility of the sealer. Zinc oxide eugenol sealer with ACA showed higher antibacterial activity as compared to the AH Plus sealer with ACA. Zinc oxide eugenol sealer with ACA have higher solubility in distilled water but within the limits of BS EN ISO 6876 (2001) standards when compared with AH Plus sealer with ACA.