MORPHOLOGY AND ELASTIC PROPERTIES OF ERYTHROCYTES SURFACE IN FROGS

The author has studied the features of morphology and elastic properties of native erythrocytes in frogs with the use of the atomic force microscopy method. On the model of adrenal load, the study demonstrated the increase in the stiffness of cells by 64% (p<0.05) accompanied by the decrease in the number of globular structures on the membrane of erythrocytes by 50% (p<0.05), and their height was increased by 254% (p<0.05) as compared to a control set. In the parallel experiments with antagonist adrenaline ? propranalol, the study has not revealed any significant differences in the morphology and elastic properties of the surface. The discovered relationship between elastic properties and morphology of the surface can be used as a diagnostic criterion in the evaluation of the functional state of the cell.