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THE STRUCTURAL AND FUNCTIONAL STATUS OF MITOGEN-TRANSFORMED LYMPHOCYTES
Journal: Research Result Journal. Physiology (Vol.1, No. 1)Publication Date: 2014-09-30
Authors : SLADKOVA E.A.;
Page : 12-20
Keywords : lymphocytes transformation; mitogen; elastic properties; surface charge; surface form; atomic-force microscopy.;
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Abstract
The new data on the structure and properties of mitogen-transformed lymphocytes’ was obtained using the methods of atomic-force microscopy. The study demonstrates that Con-A-stimulated cells have grooves in the plasmalemma with the predominance of large globules. Their stiffness and potential surface increase simultaneously. The discovered structural and functional features of proliferating in vitro lymphocytes can be used as a model in the studies of tumor blood cell degeneration.
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