Anti-inflammatory activity of the aqueous extract of Daniellia oliveri (Fabaceae)

Daniellia oliveri is a common plant in Africa and widely used by the population. It is found in the wooded savannahs as well as in dry forests. The medicinal properties of Daniellia oliveri are attributed to its different parts. Thus the leaves are used to treat various diseases such as inflammation, fever and pain. The comparative study of the aqueous extract of leaves Daniellia oliveri and the indomethacin (INDOCID) on inflammation induced by carrageenan on the right hind paw of the rats showed anti-inflammatory properties of this extract. The phytochemical analysis of the aqueous extract of leaves Daniellia oliveri showed the presence of flavonoids which could cause anti-inflammatory properties of this extract. The toxicological study of aqueous extract of leaves of Daniellia oliveri allowed to determine an LD50 = 436.51 mg/kg body weight. According Classification of Diezi this plant is toxic. These results justify the traditional use of leaves of Daniellia oliveri as anti-inflammatory.