AGE-PERTAINING MORPHOLOGIC CHARACTERISTICS OF THE HUMAN CECAL GLANDULES

Density of distribution, estimation, sizes, topography of the cecal glandules have been studied on the post-mortem material of neonatals (10 cases), adults of 22-35 years and the elderly of 60-74 years (10 and 8 cases, respectively). The total number of glandules in the walls of the cecum, basing on our material, in neonatals, reaches on average 320,000, in adults aged 22-35 and 60-74 years is estimated 490,000 and 420,000, respectively. The length of the glandules in neonatals reaches, averagely, 125 um, while in medium and elderly ages it averages 212 um and 177 um, respectively. The density of distribution of the large instestine's glandules in the area of the ileocecocolic sphincter (Busie's sphincter) in neonatals equals, on average, 57,6 glandules per 1 sq.mm, that is 1,5 times as high as in the area of the cecal cupola. In adults of 22-35 age and 60-74 age groups the density of the glandular distribution increases up to 67,7 and 62,6 per sq. mm. The length of a glandula in the sphinctefal zone in the neonatal period equals averagely 155 um, in the age of 22-35 - 560 um, in the age of 60-74 - 450 um, that is 1,3 and 2,7 times as high as, respectively, the same parameters typical for the adult periods (outside the sphincteral zones). In the neonatal period lymphoid nodules are only episodically revealed beside colonic glandules (in 15-20% of cases). In this period a diffuse lymphoid tissue beside the glandules is defined as individual cells of the lymphoid series located near the basal part of the glandules. As for individuals aged 22-35 years a lymphoid tissue is always present beside the basal part of the glandules as lymphoid nodules and as a rim around the glandule. Density of location, quantity, sizes, topography, caecum's glandules were studied on materials which were got from the cadavers of newborns (10 observations) the cadavers of people 22-35 years old (10 occasions) and also the cadavers of people 60-74 years old (8 occasions). General number of glandules in the walls of caecum is 320 thousand in neonatal period, on an average, 490 thousand in 22- 35 years old and 420 thousand in 60-74 years old. These facts are on our materials. Length of glandules is a 125 micrometers in neonatal period, 212 micrometers in mature age and 177 micrometers in elderly age. Density of location of caecum's glandules, on an average, is 57,6 glands on 1 sq. mm in region of Buzi's sphincter, for newborns. It's 1,5 times bigger than it is in area cupula of caecum's glandules. People 22-35 years old have density of location glandules 67,7. And people 60-74 years old have 62,6 glands. Length of glandules, on an average, is 155 micrometers in area of sphincter. It is for newborns. Length of glandules on an average is 560 micrometers for mature age. And length of glandules is 450 micrometers for elderly. This indicator is 1,3 and 2,7 times bigger than for elderly age on zone without sphincters. The lymphoid nodules are revealed near caecum's glandules only sometimes (in 15-20% case of newborns). This diffuse lymphoid tissue consists of single cells lymphoid layer. Cells are situated near basal part glandules. Lymphoid tissue is present permanent near basal part glands. It is for people 22-35 years old. Lymphoid tissue forms lymphoid nodules and border near glandules.