IN - SITU OPHTHALMIC DRUG DELIVERY SYSTEMS ? AN OVERVIEW

Eye is the most vital organ of the body. To achieve effective ocular therapy, an adequate amount of active ingredients must be delivered and maintain at the site of action within the eye. Ocular drug delivery is the most challenging and interesting field for the pharma scientists due to the unique anatomy of the eye. The major disadvantage of ocular drug delivery is lachrymal drainage of the drug leads to poor bioavailability. Since Conventional delivery systems often result in poor bioavailability and therapeutic response because of high tear fluids turn over and dynamics cause rapid elimination of the drug from the eyes. dendrimers, There are various new dosage forms like insitu gel, collagen shield, minidisc, ocular film, ocusert, nanosuspension, nano particulate system, liposomes, niosomes, dendrimers, ocular iontophoresis etc. Key words: In-situ gel, ocusert, liposomes, niosomes, dendrimers, iontophoresis.