THE ROLE OF SOME ACUTE PHASE PROTEINS IN DEVELOPMENT OF INTOXICATION SYNDROME

The article deals with the results of study of a state of acute phase proteins (APP) in patients having hemorrhagic fever with renal syndrome (HFRS). It was revealed that in the case of middle-type HFRS under intoxication APP metabolism changed to a considerable extent. In blood serum of such patients the level of albumin, prealbumin and transferrin decreased and haptoglobin concentration increased. In the course of the study the authors discovered, that studied APPs took an active part in activation of the systemic phase of intoxication syndrome.