THE RESEARCH OF ENDOTHELIO- AND CARDIOPROTECTIVE EFFECTS OF LAMOTRIGINE IN EXPERIMENTAL ENDOTHELIAL DYSFUNCTION
Journal: I.P. Pavlov Russian Medical Biological Herald (Vol.10, No. 2)Publication Date: 2009-06-30
Authors : Luchkina E.V.; Ershov I.N.; Pokrovskiy M.V.; Pokrovskaya T.G.;
Page : 58-62
Keywords : ;
Abstract
In laboratory animals in nitric oxide deficiency modelling introduction of NO-syntase non-selective inhibitor of L-NAME endothelio- and cardio tropical effects of lamotrigine and valproic acid investigated. Coefficients of endothelial dysfunction, myocardial loading tests are used. Endothelio- and cardioprotective effects of lamotrigine and endothelioprotective effects of valproic acid are revealed.
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