Orientation and composition of collagen fibers within the scar after myocadial lesion in rat fetuses
Journal: I.P. Pavlov Russian Medical Biological Herald (Vol.10, No. 3)Publication Date: 2009-09-10
Abstract
This study was undertaken to examine orientation and composition of collagen fibers within the myocardial scar after mechanical injury in 16-day-old rat fetuses and in adult male rats. Measurements were performed from 7 to 40 days after lesion. Angles of fiber bundles relative to the longitudinal axis of wound channel were measured and were analyzed with circular statistic techniques. Proportion of collagen types I and III was determined when studying sections stained with picrosirius red under polarized light. In adult myocardium fibers of collagen type I were abundant and longitudinally aligned, the lesion developed into a mature scar. Fetal scar contained thinner fibers, which did not display a homogeneous distribution. This suggests that fetal scar is immature, its mechanical strength is less and that fetal myocardium shows incomplete repair.
Other Latest Articles
- The program interface ?Pharmaceutical economic safety?
- THE DEVELOPMENT OF THE OPTIMUM EXSTRACTION TECHNOLOGY OF THE REGULATOR ALBUMEN WITH THE GEPATO-PROTECTORS ACTIONS FROM BIOTECHNOLOGICAL RAW MATERIAL
- In the article are presented technology of transcutaneous rhinoplastic in posttraumatic deformations of the external nose with hypertrophic cicatrixes. Advantages of this operation were demonstrated and method of making was described detaily
- Rhinoseptoplasty in сombined deformations nose with hypertrophic cicatrixes
- SYSTEMATIC MEDIASTINAL BILATERAL LYMPH DISSECTION IN LUNG CARCINOMA TREATMENT: SURGICAL APPROACH PERFECTION
Last modified: 2016-03-23 05:07:56