Clinical-physiological characteristics of diabetic polyneuropathy in pregnancy

Materials and methods. The study included 22 pregnant women suffering from diabetic neuropathy. 14 women were diagnosed with type 1 diabetes, and 8 - type 2 diabetes. The average duration of the diabetes in women with type 1 diabetes was 14,6±6,4 years, in women with type 2 diabetes 6,6±3,1 years. Authors applied the scales NSS, NDS, electroneuromyography for diagnostic of diabetic neuropathy. Complex neurological and instrumental examination was carried out on terms 15 and 32 weeks of pregnancy. Results. During pregnancy showed deterioration of subjective symptoms, an increase of neurological deficit, which was manifested increase in the average score of NSS, NDS in the 3rd trimester of pregnancy (p<0,05). Analyzing the electroneuromyography characteristics was detected a significant decrease the amplitude of motor unit potential of n. peroneus and sensor unit potential of n. suralis in pregnant women suffering from type 1 diabetes mellitus (p<0,05). Conclusions. Pregnancy is a risk factor for the progression of diabetic neuropathy and leads to a more rapid damage of axons of peripheral nerves.