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Pharmacokinetic of simvastatin at experimental hypothyreosis

Journal: I.P. Pavlov Russian Medical Biological Herald (Vol.12, No. 4)

Publication Date:

Authors : ; ;

Page : 38-42

Keywords : ;

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In article data of the research devoted to studying of pharmacokinetic of simvastatin at experimental hypothyreosis are resulted. It is shown changes of pharmacokinetic parameters of main metabolite of drug ? β-hydroxyacid of simvastatin, which says about decrease of bioavailability and correlation of these changes with level of T4.

Last modified: 2016-03-29 03:00:49