RESEARCH OF THE INDICATORS OF THE OXIDATIVE STRESS IN THE OSTEOARTHROSIS OF THE BLOOD

Complex laboratory examination of patients of the different diseases of the knee joint osteoarthrosis was detected the regularity of metabolic disorders in the form of the activation of the prooxidativ system and the inhibition of enzymatic part of the antioxidativ system. The correlation between the degree of the oxidative stress and the severity of clinical manifestations of the osteoarthrosis was established. The most relevant clinically indicators of blood for laboratory diagnosis of the osteoarthrosis such as the aliphatic aldehyde groups of the oxidated proteins and the activity of the paraoxanase were identified.