MORPHOLOGICAL CHANGES OF THE TRACHEA, BRONCHI AND LUNGS OF MICE WITH LONG EXPOSURE OF CHEMICALS PRESENT IN THE AIRSPACE OF MANNED SPACECRAFTJournal: I.P. Pavlov Russian Medical Biological Herald (Vol.13, No. 3)
Publication Date: 2012-09-29
Authors : Oganesyan M.V.; Ponomarenko E.A.;
Page : 23-27
Keywords : ;
It was conducted the morphological study of chronic exposure MPC of chemicals (acetone, acetaldehyde, ethanol) of airspace of the spacecraft on the trachea, bronchi and lungs within 70 days in male mice line of F1 (CBA x C57Bl6). At morphometric study at experimental group of mice are revealed foci of fibrosis and hyperplasia of lymphoid tissue in the wall of the trachea and bronchi, in the lungs are marked elevation of lymphoid accumulations in the wall of the main and lobar bronchi and around blood vessels. The mechanisms of development of pathological changes in the respiratory system under the influence of small doses of chemicals are discussed.
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