Immunohistochemical characteristics age transformation of the cell phone mastoid brain people of different sexJournal: I.P. Pavlov Russian Medical Biological Herald (Vol.13, No. 4)
Publication Date: 2012-11-30
Authors : Pavlov A.V.; Saveljev S.V.;
Page : 12-16
Keywords : ;
Age-related changes in the structure of the human brain mamillary bodies were found in different age and sex. In elderly and senile age there is a decrease of GFAP-immunopositive cells. This process leads to an involutive transformations of neurons in the appropriate age. From 45 years of age in the mamillary bodies NSE-immunopositive cells are located around blood vessels in both sexes. Such an arrangement may be due to age-related changes in hemodynamics this structure. Reducing the number of MBP-immunopositive fibers in the elderly explains violation of synaptic connections both within the mamillary bodies and beyond. The observed changes in the expression of selected neuronal markers indicate age involution of mamillary bodies in both sexes.
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