PHARMACOTHERAPY OF PULMONARY HYPERTENSION DURING PREGNANCY AND POSTPARTUM PERIOD

Pregnancy in women with pulmonary hypertension is associated with a high risk of poor outcomes and high maternal mortality rates, therefore contraindicated in this category of patients. Yet the world has accumulated some experience of pregnancy in women with pulmonary hypertension, who refused abortion, or in whom the disease was diagnosed in later stages of gestation. In this paper results of randomized and observational studies of the main and supportive pharmacotherapy in pulmonary hypertension are given, characteristics of modern drugs for the treatment of pulmonary hypertension and data on their safety during pregnancy are recommended, as well as expert opinion on drug therapy in pregnant women with pulmonary hypertension.