TO THE MECHANISM OF ACTION OF NEW ANTIHYPOXIC COMPLEX COMPOUND OF ASCORBIC ACIDJournal: I.P. Pavlov Russian Medical Biological Herald (Vol.14, No. 2)
Publication Date: 2013-06-28
Authors : Novikov V.E.; Markova E.O.; Parfenov E.A.;
Page : 59-65
Keywords : ;
In the experiment on rats a new derivative of ascorbic acid with antihypoxic activity was learned. It is shown that a dose of 100 mg / kg in normoxia and after exposure to acute hypoxia, it reduces the activity of free radical oxidation, has no effect on the hemogram, but leads to a significant reduction of ALT, AST, alkaline phosphatase, LDG, the level of uric acid and total protein after acute hypoxia, which is of some importance in its hypoxic effect.
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