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The ifluens of new oxypyridine derivative on the development of toxic hepatitis

Journal: I.P. Pavlov Russian Medical Biological Herald (Vol.22, No. 4)

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Authors : ;

Page : 54-60

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In conditions of experimental toxic lesion of the liver, hepatoprotective effect of the original chemical compound 2,6-dimethyl-3-oxypyridine adamantane carboxylate has been investigated. It has been shown that this compound effectively reduces the activity of liver enzymes (aspartic and alanine transaminases, lactate dehydrogenase), the content of total bilirubin and activity of free radical oxidation initiated by CCl 4 intoxication. The protective action of the substance on the liver function has been confirmed morphologically.

Last modified: 2016-03-30 08:40:47