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Features of immune system at elderly patients after splenectomy in the next postoperative period

Journal: I.P. Pavlov Russian Medical Biological Herald (Vol.23, No. 1)

Publication Date:

Authors : ; ; ;

Page : 115-119

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In order to investigate changes in the immune status of elderly patients after a splenectomy concerning an injury of a spleen researches of the immune status of 21 elderly patients which age from 60 to 80 years (the main group 1) after the injured spleen operations in the next postoperative period on the third - the fifth postoperative days was created. The group of comparison was made by 19 healthy elderly patients (group of comparison 2) and 19 patients of young and middle age (group of comparison 3). All patients had the isolated injuries of a spleen, easy volume of blood loss (to 500 ml). As a result of research it is established that at patients of advanced and senile age after a spleneetomy the following changes in the immune status of an organism in the next postoperative period are noted. In a cellular link - decrease in all analyzed indicators. In a humoral link - considerable decrease in indicators of IgG and M, FNOa, IL1ß, IL-6, INFγ and significant increase in the circulating immune complexes.

Last modified: 2016-03-30 17:10:27