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VINCRISTINE AND VINBLASTINE: A REVIEW
Journal: International Journal of Medicine and Pharmaceutical Sciences (IJMPS) (Vol.6, No. 1)Publication Date: 2016-02-29
Authors : ASHUTOSH KUMAR;
Page : 23-30
Keywords : Madagascar Periwinkle; Vincristine; Vinblastine; Tubulin; Cell Division;
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Abstract
Vincristine and vinblastine are originally derived from the periwinkle plant Catharanthus roseus . Vincristine and vinblastine act as inhibitors during the metaphase of the cell cycle and by binding to the microtubules inhibit the development of the mitotic spindle.
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Last modified: 2016-04-08 16:31:51