Emulgels: A Novel Topical Drug Delivery System

Skin is most liable to have microbial or fungal infections. Emulsions are gellified emulsion in which emulsion is incorporated into gel base. Skin is having different layers like dermis, epidermis and stratum corneum and different sub layers. Emulgels having advantages like Better stability, Hydrophobic drugs can be easily incorporated into gels using d/o/w emulsions, Production feasibility, low preparation cost, Better loading capacity, Controlled release and No intensive sonication with certain? disadvantages like poor penetration, skin irritation, bubble formation. Emulgels are of two types micro emulsion gels and nano emulgel. Emulgels are prepared contains aqueous phase made up of water or alcohols, Oil phase made up of mineral oil in combination with soft paraffin or hard paraffin, emulsifiers, gelling agents, anti-oxidants, preservatives, penetration enhancer and humectants. Emulgels are characterised? for parameters such as Physical Examination, Rhelogical Studies, Globule size and its distribution in emulgel, Spreading Coefficient, Extrudability Study of Topical Emulgel (Tube Test), Swelling Index, Drug Content Determination, Skin Irritation Test (Patch Test), Ex?Vivo Bioadhesive strength measurement of topical emulgel, In-Vitro Release Study, Microbiological assay, Drug Release Kinetic Study, Stability Studies and Accelerated stability studies of Gellified Emulsion.