Autonomic Dysfunction in Acromegaly: A Case Report

Orthostatic hypotension commonly presents in patients with chronic illnesses like hypertension, diabetes mellitus, chronic kidney disease and LV dysfunction. Autonomic dysfunction is often overlooked as a cause for orthostatic hypotension that can lead to increased morbidity and mortality. Though autonomic dysfunction on electrophysiological testing has been described in patients with acromegaly, symptomatic dysautonomia resulting in orthostatic hypotension has not been previously reported in literature. Here we present a case of acromegaly who presented with postural hypotension. RR variability based clinical tests showed presence of autonomic insufficiency. His symptoms improved with conservative measures.