Development of Hemosomal Drug Delivery System

Haem is found in all living cells as well tissues in the form of proteins such as cytochromes, hemoglobin’s and peroxides. This is act as catalyst for the formation of oxygen radicals. Encapsulation of haem or hemoglobin with in lipid vesicles or liposome’s is called “Hemosomes” or it is also called Liposome-encapsulated hemoglobin (LEH). Which are 0.1 to 10 microns in dimension, and it is a technology of preparing artificial red blood substitutes. The synthetic cells are stable being somewhat smaller and stronger than normal red blood cells and are having same electrophoretic movements. Hemoglobin (Hb) encapsulation within a liposome is one of the strategies in the development of artificial oxygen carriers. The review article includes preparation techniques, characterization and stability of Hemosomal drug delivery system.