Aglepristone efficiency with and without the canine pyometra cloprostenol
Journal: REVISTA MVZ CÓRDOBA (Vol.20, No. 2)Publication Date: 2015-05-01
Authors : Víctor Molina D;
Page : 4636-4645
Keywords : Antiprogestins; estrogens; endometrial hyperplasia; bitch; progesterone; prostaglandin;
Abstract
Objective. Evaluate the effectiveness of aglepristone with and without cloprostenol for treating canine pyometra. Materials and methods. Ten female French Bulldogs between 3-8 years of age diagnosed with pyometra were divided into two groups, one receiving a 10 mg/kg dose of aglepristone subcutaneously on days 1, 2, 8, 14 and 28, and the other an equal dose on days 1, 3, 8 and 15, as well as a 1 ?g/kg dose of cloprostenol subcutaneously on days 3 and 8. Both groups received 5 mg/kg of enrofloxacin orally every 12 hours for 28 days. Hematic profiles were generated on days 1 and 28 and counted days until the next heat, expelling purulent material and of clinical recuperation. Results. There was no statistical difference in the variables of the line red blood cells between times and protocols. The line of white blood cells showed a statistical difference between days of treatment but not between the two groups. Both treatments were effective resulting in complete clinical recuperation. The combination of aglepristone with cloprostenol acted more quickly, decreasing the number of days of secretion, abdominal pain, and the recuperation of normal activity and appetite. All 10 females were bred during their first heat. Three females from the aglepristone group and one from the combined aglepristone with cloprostenol group were impregnated. Conclusions. Both protocols, combined with enrofloxacin, produced complete clinical recuperation in bitches with pyometra, but it was achieved more rapidly when given the combination of both aglepristone and cloprostenol.
Other Latest Articles
- Estimation of milk production in hair ewes by two methods of measurement
- Evaluation of macrominerals concentrations in blood of lactating and dry Desi cows
- Profile of canine patient with esophageal foreign bodies
- Serological evidence of Hepatitis E Virus infection in Antioquia, Colombia slaughtered pigs
- Physiology of acid-base balance in bovines with diarrhea backgrounds from Monteria, Colombia
Last modified: 2016-06-24 02:25:10