A Short Synopsis of the Current Status of Double-Stranded RNA-Mediated Immunokilling for Gastrointestinal Cancer
Journal: Austin Journal of Gastroenterology (Vol.1, No. 1)Publication Date: 2014-05-29
Authors : Jin B; Yeo AET;
Page : 1-4
Keywords : Double-stranded RNA; Gastric cancer; Colorectal cancer; Immunotherapy; Toll-like receptor 3;
Abstract
Significant advances in cancer immunotherapy have been made in recent years and one such tool is the use of double-stranded RNA (dsRNA) which is the molecular pattern of virus infection which are recognized by pattern recognition receptors. The combination of dsRNA and its receptors induce a significant immune response and trigger cancer cell apoptosis in vivo. In this paper, the use of dsRNA in immunotherapy of gastrointestinal cancer is briefly reviewed.
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