Single dose of secnidazole treatment against naturally occuring Giardia duodenalis infection in Sakiz lambs
Journal: REVISTA MVZ CÓRDOBA (Vol.19, No. 1)Publication Date: 2014-01-01
Authors : Kerem Ural; Nuran Aysul; Huseyin Voyvoda; Bulent Ulutas; Osman S. Aldemir; Hasan Eren;
Page : 4023-4032
Keywords : Clinics; evaluation; lamb; secnidazol;
Abstract
Objetive. The purposes of this study were to determine whether secnidazole administered at a single dose of 10 mg/kg, orally, lessens or eliminates Giardia cyst shedding, and to validate the benefit of secnidazole treatment on clinical signs and faecal consistency in lambs naturally infected with Giardia duodenalis. Materials and methods. To this extent weaned 12 weeks of age lambs were selected and randomly assigned into two groups based on placebo (group C, n=7 untreated control group) or treatment (group S, n=10 lambs treated with a single dose of secnidazole at 10 mg/kg). Results. On days 0 and 10, before and after treatment, respectively, reduction in cyst excretion was determined. The faecal consistency and general health were recorded at each sampling day. Conclusions. During the study there was a high (99.98%) reduction in cyst excretion in the secnidazol treatment group compared to the positive control group on day 10, resulting in a significant (p<0.001) reduction, making secnidazole highly effective treatment option.
Other Latest Articles
- Application of the logistic model to describe the growth curve in dogs of different breeds
- Evaluation of the physicochemical and functional properties of Colombian bee pollen
- Relationship between apoptosis and the BH2 domain sequence of the VP5 peptide of infectious pancreatic necrosis virus
- Some ecological aspects of free-living Haemaphysalis juxtakochi Cooley, 1946 (Acari: Ixodidae) in Panama
- Risk factors for ovarian postpartum resumption in Holstein cows, under high tropical conditions
Last modified: 2016-06-29 00:13:22