Glanzmann’s Thrombasthenia: Role of Angioembolization and factor VII in recurrent bleeding from ulcerated duodenum
Journal: INTERNATIONAL JOURNAL OF ENDORSING HEALTH SCIENCE (IJEHSR) (Vol.4, No. 2)Publication Date: 2016-06-30
Authors : Ali Abbas; Raza Sayani; Syed Muhammad Mustahsan; Anwar Saeed;
Page : 17-21
Keywords : Glanzmann’s thrombasthenia (GT); functional disorder of platelets; angioembolization; bleeding diathesis;
Abstract
Introduction: Glanzmann’s thrombasthenia (GT) is a rare, genetically inherited, functional disorder of platelets. The pathology is deficient or dysfunctional platelet glycoprotein IIb/IIIa (GP IIb/IIIa) complex resulting in bleeding diathesis. Case Report: Here in, we report the effectivity of angioembolization with factor VII in a patient with Glanzmann’s thrombasthenia (GT), who presented with recurrent bleeding from duodenal ulcer. Conclusion: Angioembolization with added infusion of factor VII, can be considered an equally effective alternate to platelet transfusion in patients of GT, who present with recurrent bleeding.
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