Multiple Myeloma and Chronic Myelogenous Leukemia; an Uncommon Coexistence in 2 Patients, with Literature Review

The coexistence of Multiple Myeloma (MM) and Chronic Myelogenous Leukemia (CML) is an extremely uncommon event that has only been reported in very few cases. Here, we present 2 new cases of concurrent MM and CML. The case of 63 year old woman with CML, who was treated with imatinib mesylate and subsequently developed MM 6 years after the diagnosis of CML, and the case of a 68 year old man with MM, who was treated with radiation therapy and chemotherapy and subsequently developed CML 4 years and 7 months after the diagnosis of MM. The relationship between CML and MM, is also discussed.