Granulocytic Sarcoma Involving the Gynecologic Tract: One Case Report and Review of the Literature

Granulocytic sarcoma is an extramedullary tumor associated with acute myeloid leukemia (AML). It is rarely seen in the female tract. We report an unusual case of granulocytic sarcoma of the uterus in an AML patient who relapses after 14 years of first complete remission. A mixed-lineage leukemia (MLL) gene rearrangement supports the association of that malignancy with prior chemotherapy. Second line therapy consisted in chemotherapy, radiation, and allogeneic stem cell transplantation.