The effect of Medroxy Progesterone Acetate on adrenal gland of Indian Palm Squirrel Funambulus pennati (Wroughton)

For many years research in the field of contraception or the application of contraceptive methods has been exclusively limited to female as compared to male fertility control. The most highly effective reversible contraceptive method for men with no side effects has yet to be developed. Administration of several progestational compounds has been shown to inhibit spermatogenesis. Although progesterone is studied extensively, the exact mechanism of action of this compound has not been proven. The present experiment was designed to determine the exact relationship between the pituitary-gonad and adrenal following the intramuscular injection of Depo-Provera to male squirrels Funambulus pennati (Wroughton). The proposed investigation will contribute to the understanding of pituitary-gonad-adrenal relationship and the results will be of considerable importance in contraceptive study