Prevalence of asymptomatic bacteriuria and its antibiotic sensitivity in type-2 diabetic women along the sea coast

Type-2 diabetes women are more prone for Urinary tract infections (UTI). Many UTIs are asymptomatic and whether the symptomatic UTI are preceded by asymptomatic bacteriuria (ASB) is not clear. Hence, the present study is conducted to understand the relationship between ASB and symptomatic UTI among Type-2 diabetic women along the sea coast.A hospital based study conducted in the Narayana Medical College & Hospital, which is situated within 10-15 km radius of the seacoast in Nellore district of Andhra Pradesh, India. 238 subjects were selected, out of these 164 diabetic subjects in the experimental and 56 in the control group. Findings indicate that the prevalence of ASB in type-2 diabetic women is high along the sea coast and significantly associated with nephropathy. The major risk factors include age, duration of diabetes, proteinuria, leucocyturia, glucosuria, nephropathy and rise in plasma glucose. Among the clinical isolates of ASB, gram negative isolates were more than gram positive. These isolates are highly resistant to antibiotics like Ciprofloxacin, Ofloxacin, Gentamicin and Cefotaxime while, sensitive to Amikacin and Cephaperazone ± sulbactam. Thus present study concludes that overall risk factors for ASB in type-2 diabetic women observed are proteinuria, leucocyturia, glucosuria, nephropathy and plasma glucose. [Int J Res Med Sci 2013; 1(4.000): 487-495]