EMERGENCIES IN MULTISYSTEM ATROPHY

Abstract : Background MSA is a neurodegenerative disorder associated with Parkinsonism, cerebellar ataxia, and autonomic dysfunction. Pituitary apoplexy is an endocrine emergency. Association between these two has not been not described so far. The occurrence of stridor and sleep apnoea in patients with MSA is associated with decreased life expectancy.Cases We present 2 cases of emergencies in multisystem atrophy.1.Pituitary apoplexy in Multi system atrophy-parkinsonism type(MSA-P) 2.Nocturnal stridor in Multi system atrophy-cerebellar type(MSA-C) Conclusion Pituitary apoplexy in Multi system atrophy-parkinsonism type is presented for its unusual association. Hypotension due to dysautonomia is the cause for pituitary apoplexy. Polysomnography and laryngoscopy are the important diagnostic tools for nocturnal stridor in MSA. Bilateral vocal cord paresis (or) dystonia is the cause for stridor and respiratory compromise. Permanent tracheostomy is the treatment option for this patient.