AN ANALYSIS OF SOLID PSEUDOPAPILLARY NEOPLASMS OF PANCREAS - 10 YEARS EXPERIENCE IN A TERTIARY CENTRE

Background - Solid pseudopapillary neoplasm (SPN) is a rare tumour with low malignant potential comprising 0.13 to 2.7 of all pancreatic tumours. The aim of this study was to analyse clinical and pathologic characteristics and surgical outcomes of SPNs. Methods - Clinical data from 2001 to 2010 were retrospectively analysed for SPN. Thirteen cases of solid pseudo papillary tumours were reported in our institute. Clinical and pathological features, radiological findings, surgical intervention, follow up details were reviewed.Results - Total number of SPN was thirteen. Twelve patients were female (92 percent). Median age of presentation was 23 years. Predominant symptom was abdominal pain (69 percent). Ten patients (77percent) presented with solid cystic component. Three were solid tumours. Preoperative diagnostic possibility of SPNs was considered in eight patients (61.5 percent) on basis of clinical radiological findings. Radiological features suggestive of malignancy were seen in two. Two patients were diagnosed as SPN by FNAC. Eleven patients (84.6 percent) underwent complete resection ( distal pancreatectomy 9 , central pancreatectomy 2 ) . One patient underwent palliative resection. Another one was inoperable and received palliative chemotherapy. On follow up( 6 months to 10 years ), patients who underwent complete resection did not develop recurrence. Patients who underwent palliative chemotherapy, died after twenty two months due to advancement of the disease . Patient who underwent palliative resection was on regular follow up. Conclusion - Preoperative diagnosis of SPN is crucial in order to propose the proper management . Offering palliative resection gives better results and associated with long term survival even in advanced SPNs.