ASSOCIATION OF CORONARY ARTERY DISEASE WITH PSORIASIS IN A GROUP OF PATIENTS IN QUEEN ALIA HEART INSTITUTE (QAHI) in Jordan

O bjective: The aim of our study is to demonstrate the association between psoriasis and CAD in a group of patients at QUEEN ALIA HEART INSTITUTE (QAHI). Methods: This retrospective study was conducted at QUEEN ALIA HEART INSTITUTE from April 2012 to August 2016. 167 psoriatic patients (with moderate to severe psoriasis) and 197 non - psoriatic patients (control group) were matche d by sex, age and risk factors of CAD. All patients underwent coronary angiography, and the incidence of coronary artery disease was compared between the two groups. Results: After analysis, the p - value of CAD risk factors in both groups (psoriasis and con trols) were: age (41.3 year, 35.4 ,0.04) , male (67% , 64% ,0.06), smoking (60.5% , 56% , 0.4) , HTN (40.5 % , 43% , 0.29 ) ,DM (37.5% ,36.3% ,0.3), hyperlipidemia (20.3% , 17.8% , 0.41), family history (36.1% ,34..4 ,0.05). After matching for all these ri sk factors, the rate of CAD in psoriasis patients was (8.2%) and (2.1%) in non - psoriatic patients with p - value less than 0.001. Conclusion : Psoriasis (moderate and severe) is an independent risk factor for increasing the risk of coronary artery disease in (sex, age, and other risk factor for CAD) matched patients. CAD: CORONARY ARTERY DISEASE