ROLE OF CONTINUOUS RENAL REPLACEMENT THERAPY (CRRT) IN SEPTIC ACUTE KIDNEY INJURY PATIENTS

Background The systemic inflammatory response syndrome (SIRS) and sepsis are complex syndromes resulting from an inciting insult that causes systemic inflammation, leading to widespread tissue injury mainly acute kidney injury AKI. It's an overwhelming inflammatory and coagulopathic response to a source of infection, usually from the lung or abdomen. If not recognized early, or not treated properly and aggressively, it is often a lethal outcome. Objectives: To determine the therapeutic efficacy and safety of continuous renal replacement therapy (CRRT) in the treatment of Patients with septic AKI. Patients and Methods This is cross sectional study were 43 patients with sepsis & acute kidney injury included and they were undergo management by using (CRRT plus conventional therapy) in intensive care unit (ICU) of Ghazi Al Hariri teaching hospital in a period from August 2014 to April 2015. Results : Our study showed that 23 out of 43 patients with septic AKI who were treated by continuous renal replacement therapy CRRT were improved and 20 patients were not get benefit of treatment (died). Conclusions CRRT is an important adjuvant to conventional treatment to reduce mortality in patients with septic AKI.