A CURSORY GLANCE ON BIOMARKERS FOR BONE IN HEALTH AND DISEASE

Periodontitis, an inflammatory disorder is characterized by soft tissue as well as hard tissue destruction. Biochemical markers of bone remodeling provide clinically useful evidence of the normal and pathologic processes that reflect bone cell activity in the periodontium. There is this major challenge always in clinical periodontics to find a reliable molecular marker of periodontal tissue destruction with high sensitivity, specificity and utility. This review article enumerates various biomarkers responsible for bone destruction whose presence and absence can guide a clinician with the periodontal disease activity taking place.