Metachronous Metastasis to Glans Penis from Colorectal Cancer

Penile metastases from rectal adenocarcinoma are rare and usually develop after the prime tumor has manifested. They suggest disseminated disease and are associated with poor prognosis. They can develop very late in the clinical course of metastatic cancer and the clinical presentation can be very inconspicuous. Clinicians need to be aware of this late presentation. We present the case of a 78-year-old patient, who first appeared to our department with a symptomatic, fleshy, red papule on his glans penis, which looked like pyogenic granuloma. There had been a diagnostic conundrum. However, his past medical history suggested that his condition was clinically consistent with a cutaneous metastasis. That is the reason why we performed an urgent biopsy, which confirmed our diagnosis. Clinicians need to be aware of penile metastases' occurrence and undertake appropriate imaging and biopsy before treatment.